pks+ Escherichia coli more prevalent in benign than malignant colorectal tumors
Abstract
Some E. coli strains that synthesize the toxin colibactin within the 54-kb pks island are being implicated in colorectal cancer (CRC) development. Here, the prevalence of pks+ E. coli in malignant and benign colorectal tumors obtained from selected Filipino patients was compared to determine the association of pks+ E. coli with CRC in this population.
Keywords
clbA; clbB; clbN; colorectal cancer; pks + E. coli.